A within-host mathematical model to describe the dynamics of target cells and viral load in early HIV-1 infection was developed, which incorporates a combination of RTI and PI treatments by using a pharmacokinetics model. The local stabilit……
A within-host mathematical model to describe the dynamics of target cells and viral load in early HIV-1 infection was developed, which incorporates a combination of RTI and PI treatments by using a pharmacokinetics model. The local stability of uninfected steady state for the model was determined using an alternative threshold. The pharmacokinetics model was employed to estimate drug efficacy in multiple drug dosing. The effect of periodic drug efficacy of pharmacokinetic type on outcome of HIV-1 infection was explored under various treatment interruptions. The effectiveness of treatment…
In this study a generalization of the Riesz representation theorem on non-degenerate bilinear spaces, particularly on spaces of truncated Laurent series, was developed. It was shown that any linear functional on a non-degenerate bilinear space is representable by a unique element of the space if and only if its kernel is closed. Moreover an explicit equivalent condition can be identiï¬ed for the closedness property of the kernel when the bilinear space is a space of truncated Laurent series.
The development of breast cancer involves many processes, including angiogenesis and metastasis. Some factors play a major role in angiogenesis, such as HIF-1α, and in metastasis, such as FAK and Wnt2. The aim of this study was to observe the effect of propolis and mangostin on the development of mammary gland cancer and on the expression of Wnt2 and FAK in Balb/C mice. Mammary gland tumors were induced in Balb/C mice by DMBA. The mice were divided into 5 treatment groups: negative control (K"‘); positive control treated with doxorubicin (14.04 mg/kg bw) (Dx); mice treated with propolis…
The wireless sensor network (WSN) is an attractive technology, which combines embedded systems and communication networks making them more efficient and effective. Currently, WSNs have been developed for various monitoring applications. In this research, a wireless mesh network for a pipeline monitoring system was designed and developed. Sensor nodes were placed at each branch in the pipe system. Some router fails were simulated and the response of each node in the network was evaluated. Three different scenarios were examined to test the data transmission performance. The results proved that…
In this study, a quantitative analysis based on the color space coordinates CIE 1931 to determine the color combination from three LEDs (light emitting diode) sources and three laser sources separately, has been investigated. The light sources used in this research were three LEDs that emit blue light, green and red colors, and three laser sources that also emit blue light, green and red colors. Result of color combination from LEDs and laser light sources were detected using a spectrophotometer. The result of the light spectra were then analyzed using a set of color matching function that…
In this paper, we investigate the stability of the zero solution of an integro-differential equation of the second order with variable delay. By means of the fixed point theory and an exponential weighted metric, we find sufficient conditions under which the zero solution of the equation considered is stable.