Vol. 54 No. 3 (2023)

Hepatitis B immunoglobulin (HBIG) is an effective treatment for hepatitis B, including postexposure prophylaxis of HBV infection, prevention of HBV reinfection in liver transplant patients, and reducing sexual transmission. This study investigated the synthesis of human IgG antibodies that specifically target HBsAg subtype adr in CHL-YN cells, a newly established cell line that grows faster than CHO-K1. To achieve the synthesis of human IgG antibodies, a plasmid vector encoding DNA sequences for human IgG antibodies against HBsAg was constructed and then transiently transfected into CHL-YN…

A new limonoid, belonging to the havanensin-type, called pentandricine E (1), alongside four other known types, i.e., trichilenone acetate (2), toonaciliatones C (3), 11α-acetoxyazadirone (4) and ceramicine I (5), were found in Chisocheton pentandrus stem bark. The structures of the isolated 1-5 were identified by NMR spectroscopy and HRTOFMS. Pentandricine E (1) displayed the highest cytotoxicity toward the MCF-7 breast cancer line with an IC50 value of 63.27 ± 0.21 mM.

The relationship between phytoplankton dynamics and dissolved organic matter (DOM) in aquatic systems based on fluorophore organic matter properties results in poor implementation of methods for water quality monitoring. This study aimed to investigate the relation between fluorophore organic matter and phytoplankton index and to estimate the phytoplankton index by fluorescent organic components for water quality assessment. The research was conducted by sampling urban river water, followed by measuring the biological phytoplankton index and dissolved organic matter during the wet and dry…

We propose a simple method for 1D S-wave velocity (Vs) profile estimation using a measured surface S-wave velocity (V1) and peak frequency of the observed microtremor horizontal-to-vertical spectral ratio (HVSR). In this method, the S-wave velocity profile is presented as linear velocity increase with depth in sediments over a bedrock layer that has a given constant S-wave velocity. Thus, the profile can be parameterized with the measured surface S-wave velocity and the velocity gradient. The gradient can be estimated based on the agreement of the peak frequencies of the observed microtremor…

The measurement of nitrogen dioxide (NO2) in industrial and residential areas needs comprehensive and reliable instrumentation providing long-interference-free operation and minimum maintenance and recalibration. Differential optical absorption spectroscopy can be used as a direct measurement technique based on the specific absorption characteristics of NO2 following the Berr-Lambert law. This paper proposes a low-cost folded-path photometer to measure NO2 in the air. Cheap tubular acrylic was used as a detection cell with a 3D printed framework, making it compact, modular, and flexible.…