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A multiscale approach for spatially inhomogeneous disease dynamics
Markus SchmidtchenOliver T.C. TseStephan Wackerle
In this paper we introduce an agent-based epidemiological model that generalizes the classical SIR model by Kermack and McKendrick. We further provide a multiscale approach to the derivation of a macroscopic counterpart via the mean-field l……
The majority of an immune system infected by HIV (Human Immunodeficiency Virus) is CD4+ T cells. The HIV-1 transmission through cell to cell of CD4+ T cells supports the productive infection. On the other hand, infected CD4+ T cells stimulate cytotoxic T-lymphocytes cells to control HIV-1 infection. We develop and analyze a mathematical model incorporating the infection process through cell to cell contact of CD4+ T cells, CTL compartment and the combination of RTI and PI treatments. By means of the alternative reproduction ratio, it is analyzed the stability criteria and the existence of…
Meksianis Z. NdiiNursanti AnggrianiAsep K. Supriatna
The Differential Transformation Method (DTM) and the Non Standard Finite Difference Scheme (NSFDS) are alternative numerical techniques used to solve a system of linear and nonlinear differential equations. In this paper, we construct the DTM and NSFDS for a mathematical model of plant disease transmission dynamics and compare their solutions to that generated by MATLAB ode45 routine, which is the well-established numerical routine. The solutions of the DTM and NSFDS are in good agreement with MATLAB ode45 routine in the small time step. However, when the time step is larger, the NSFDS…
Richards model, Gompertz model, and logistic model are widely used to describe growth model of a population. The Richards growth model is a modification of the logistic growth model. In this paper, we present a new modified logistic growth model. The proposed model was derived from a modification of the classical logistic differential equation. From the solution of the differential equation, we present a new mathematical growth model so called a WEP-modified logistic growth model for describing growth function of a living organism. We also extend the proposed model into couple WEP-modified…
In this paper we introduce an agent-based epidemiological model that generalizes the classical SIR model by Kermack and McKendrick. We further provide a multiscale approach to the derivation of a macroscopic counterpart via the mean-field limit. The chain of equations acquired via the multiscale approach is investigated, analytically as well as numerically. The outcome of these results provides strong evidence of the models
A concept of an âinvisible wallâ is used here as a control mechanism to separate the human population from mosquitoes in the hope that mosquitoes gradually change their preference to other blood resources. Although mosquitoes carry inherent traits in host preference, in a situation in which regular blood resource is less available, and there are abundant other blood resources, mosquitoes may adapt to the existing new blood resource. Here we construct a model of mosquitoes preference alteration involving anthropophilic, opportunistic, and zoophilic, based on the application of repellent…