Vol. 46 No. 1 (2021)

Ascorbic acid or vitamin C is one of the most widely consumed supplement and available at the market in several preparations such as tablet, sweetlet, effervescent tablet, and ready to drink product. Spectrofluorometric method has been developed in this study for quantitative determination of ascorbic acid in various forms of products based on the reaction between ascorbic acid and methylene blue. Methylene blue concentration decreased along with the addition of ascorbic acid due to a redox reaction which caused the formation of colorless leuco-methylene blue and dehydroascorbic acid. The…

Gatot merupakan pangan olahan tradisional dari singkong yang mempunyai potensi sebagai bahan pangan pengganti, namun kualitas hasil produksi dari industri kecil sering kali kurang terjamin dan berpotensi merugikan kesehatan. Penelitian ini bertujuan untuk mengidentifikasi mikroba dan nutrisi yang terdapat dalam gatot tradisional serta serta membandingkannya dengan gatot modifikasi yang dibuat sendiri. Gatot modifikasi dibuat melalui fermentasi fase padat menggunakan pembungkus yang berbeda yaitu plastik, daun pisang dan kain. Hanya gatot modifikasi yang difermentasi dalam plastik yang…

Withdrawal symptom in alcohol dependence is one the main problems in treating alcohol addiction. This study was aimed to clarify the role of the arachidonic acid cascade in the expression of withdrawal signs in animal model of alcohol dependence. Dependence was induced by repeated administration of 15% ethanol in 0.2% sucrose solution for 17 days. On the 18th day, the ethanol was not given, and one hour after the supposed time of ethanol administration, diclofenac at 10 mg/kg was injected i.p. to induce withdrawal. Observation of behavioral withdrawal signs was performed for 30 minutes,…

Defisiensi vitamin D sering dikaitkan dengan beberapa penyakit kronis. Indonesia merupakan Negara tropis yang sepanjang tahun disinari matahari. Sinar matahari merupakan sumber terbesar vitamin D, tetapi defisiensi vitamin D masih banyak dialami di negara tropis. Sumber utama lain vitamin D merupakan makanan, perilaku konsumsi makanan yang salah pada masa remaja menyebabkan ketidakseimbangan antara konsumsi gizi dengan kecukupan gizi. Penelitian ini dilakukan untuk analisis perbedaan asupan dan faktor resiko defisiensi vitamin D dengan menggunakan metode cross sectional pada 100 mahasiswa…

The research was carried out to isolate and characterize the methyl β-orsellinate of lichen Dirinaria sp. collected from the coastal areas of Teluk Nipah, Pulau Pangkor, Perak Malaysia. The sample was extracted in methanol for three times at room temperature. Subsequently, the crude extracts and further analysed using thin-layer chromatography (TLC) and vacuum liquid chromatography (VLC). To derive the pure compounds, the isolation step was performed using radial chromatography (RC). The chemical structure of the isolated compound was determined by several spectroscopies i.e. infra-red (IR),…