Vol. 49 No. 2 (2024)

Elevated triglyceride levels can be managed through non-pharmacological approaches, including the use of moringa seeds. These seeds are rich in fatty acids that exhibit potential in reducing hyperlipidemia. This research is designed to assess the impact of moringa seed oil on triglyceride concentrations in male Wistar strain white rats (Rattus norvegicus) administered with different doses. Utilizing a Posttest-Only Control Group Design, the experiment was conducted across five groups: K1 (positive control), K2 (negative control), K3 (3 mL moringa seed oil), K4 (6 mL moringa seed oil), and K5…

Striae Gravidarum (SG) are stretch marks seen in pregnant and postpartum women. Treatments for SG aim to reduce redness and enhance pigmentation and collagen. Chemical peeling treatment can be harmful. They may cause liver, kidney, and skin issues, including inflammation and skin loss. Meanwhile, laser treatments may lead to skin inflammation for 2-4 days post-procedure. Despite this, they remain popular. Topical retinoic acid can cause birth defects and miscarriages if used in pregnancy. This highlights the need for natural treatments for SG. This study aimed to find the content and the…

Propionibacterium acne and Staphylococcus epidermidis are the major bacteria that infect skin which can cause many disease in the skin, one of them is acne. Papaya is one of the plants that has many activities, such as antibacterial activity. In traditional use, papaya leaves used for treatment of acne. In this study, the antibacterial activity of n-hexane, ethyl acetate, and ethanol papaya leaves extract were tested against Propionibacterium acne and Staphylococcus epidermidis ATCC 12228 using agar diffusion disc method, microdilution method to determine minimum inhibitory concentration…

Anemia is one of the conditions that often occurs in pregnant and lactating women when hemoglobin levels in the body are below normal, therefore pregnant and lactating women are strongly encouraged to take Blood Supplemented during pregnancy and lactation. This study was conducted to determine the incidence of anemia, the level of knowledge of respondents, the level of compliance of respondents, and to determine the effect of the level of knowledge and compliance on the incidence of anemia in pregnant and lactating women in Palu City. This research method uses a cross sectional design with…

Intervensi apoteker dalam managemen tim multidisiplin dapat mencegah maupun menurunkan masalah terkait obat atau drug-related problems (DRPs) yang berdampak terhadap perbaikan luaran klinis dan kualitas hidup pasien. Terapi stress ulcer prophylaxis (SUP) seringkali diberikan pada pasien yang menjalani perawatan di rumah sakit dan ditemukan adanya DRPs dari penggunanan obat tersebut. Review ini bertujuan untuk mengkaji intervensi apoteker dalam menurunkan drug-related problems (DRPs) pada pasien rawat inap yang mendapatkan terapi stress ulcer prophylaxis (SUP). Review ini merupakan narrative…

Diabetes has grown into a demanding global public health problem, with generally 537 million individuals afflicted worldwide. Without appropriate intervention, the risk of developing chronic complications increases. One of the practical actions for controlling type 2 diabetes mellitus is suppressing carbohydrate-hydrolyzing enzymes such as α-glucosidase. Syzygium jambos has a long history as a traditional medicine. It

Rosella flower extract is known rich in flavonoid anthocyanin that has activity as antipollutants. So it has potential to be developed as a facial cleansing products. On previous studies, the optimum formula of roselle flower extract facial wash gell and micellar water has been obtained as water-base cleansing face products. Analysis of the of chemical compounds in both formula is essential to be conducted in order to determine their flavonoid content for their quality evaluation. In the analysis process, validated method should be used to ensure the method is performed in accordance to its…

A body mass index of ≥30 kg/m2 indicates obesity, which is brought on by an excess of fat deposits. blocking obesity can be achieved in part by blocking the pancreatic enzyme lipase from doing its job. A plant belonging to the Zingiberaceae family, bangle rhizome has been used traditionally for body slimming and stomach reduction. Standardization is required to guarantee the quality of Bangle extract as a basic material for traditional medicine. The study aim were evaluate specific and non-specific character to standardize Bangle extract and to conduct the inhibitory activity of lipase enzyme…

Pain is a sign of tissue damage in the body. Extracts from the Zingiberaceae family have been proven to be hypoalgesic agents and are superior to non-steroidal anti-inflammatory drugs. The aim of the research was to determine the analgesic effectiveness of the ethanol extract of temu blenyeh (Curcuma purpurascens Blume). The analgesic effectiveness test was carried out using the writhing method (Sigmund) on male white mice (Mus musculus) as test animals. The test animals used were 25 mice grouped into 5 consecutive treatment groups, namely Group 1 (aquadest), Group 2 (antalgin), group 3 (Dose…

Resistance to antimalarial drugs has become a global challenge in achieving the target of malaria eradication. To address this issue, effective and safe alternative treatments are urgently needed. This study compares the ADMET profiles (absorption, distribution, metabolism, excretion, and toxicity) of synthetic antimalarial drugs with active compounds derived from herbal sources using an in-silico approach. The analyzed herbal compounds, including piperine, kaempferol, berberine, quassin, and limonin, demonstrated high intestinal absorption (>30%), good water solubility, and sufficient skin…