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Communication in Biomathematical Sciences Vol. 8 Issue 1 2025

Vol. 8 No. 1 (2025)

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Articles Published in This Issue

Explore peer-reviewed research articles published in this issue.

researchpp. 1–18

Optimal Control for Resource Allocation in a Multi-Patch Epidemic Model with Human Dispersal Behavior

A multi-patch epidemic compartmental model with human dispersal behavior studies the spread of the disease and it sets the model to real-world situations. The mobility matrix (M) applies human dispersal behavior to the model. The optimal control theory assists in controlling the disease burden while minimizing the cost of infected individuals and implementing control measures. We formulate a multi-patch SIR model with human dispersal behavior to control and reduce communicable disease outbreaks such as COVID-19 by optimizing resource allocation in Sri Lanka. Results are represented by using…

Keywords
Multi-patch model human dispersal optimal control effective reproduction number vaccination social distancing
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researchpp. 110–129

Mathematical Model for the Growth of Mycobacterium Tuberculosis Infection in the Lungs:

In this work, we develop a population dynamics model of Mycobacterium tuberculosis (Mtb), the bacteria responsible for tuberculosis (TB), to evaluate the impact of bacterial competition on infection prevalence. We consider two types of Mtb population growth: The first is caused by bacteria that grow inside each infected macrophage and is believed to be correlated with the number of infected macrophages; The second is that extracellular bacteria grow through self-replication. In this study, we modeled the immune response to Mtb bacterial infection in the lungs using a five-dimensional…

Keywords
Mathematical model tuberculosis Mtb bacterial immune response
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researchpp. 130–131

Erratum: Geometric Approach to Predator-Prey Model with Carrying Capacity on Prey Population

This erratum addresses inaccuracies found in the figure captions of the article titled "Geometric Approach to Predator-Prey Model with Carrying Capacity on Prey Population" [Marshellino, Tasman, H. and Rusin, R., Communication in Biomathematical Sciences, 7(2), pp. 162-176, 2024. DOI: 10.5614/cbms.2024.7.2.1].

Keywords
Predator-prey geometric singular perturbation theory fast-slow system entry-exit function
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researchpp. 19–41

A Vaccination and Isolation Strategy Based on an Adaptive Sliding Mode Control Design for the COVID-19 Virus (Omicron Variant) in Jakarta, Indonesia

The Omicron variant, identified as B.1.1.529, has been recognized as a variant of concern (VOC) by the World Health Organization (WHO), necessitating continuous monitoring and a proactive response. This study develops a mathematical model to analyze the spread of COVID-19 mutations, considering a population that, despite vaccination, remains susceptible to infection. The model also accounts for key epidemiological factors, including the incubation period, quarantine measures, and various intervention strategies. This study focuses on the epidemiological conditions in Jakarta Province, where…

Keywords
COVID-19 Omicron control strategy sliding mode control adaptive
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researchpp. 42–54

Linear Mixed Model for Oil Palm Parents Selection

The objective of plant breeding is to obtain superior seeds. These seeds originated from parents that can pass their superior traits to their progeny. The observed characteristics of the progeny (phenotype) determined the traits of these seeds. Therefore, we performed a progeny analysis. In this analysis, the data samples were collected from Riau in Sumatera and Kumai in Kalimantan (two locations). The main objective is to find superior parents from these two locations. The superiority of the selected parents lies not only in passing high production traits but also in adaptability (fit) to…

Keywords
breeding oil palm phenotype general combining ability linear mixed model
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researchpp. 55–65

An Isolation Model for Tuberculosis Dynamics with Optimal Control Application

Tuberculosis (TB) remains a persistent global health challenge, worsened by asymptomatic carriers who contribute to undetected transmission. An SIQR mathematical model that classifies infected individuals into symptomatic and asymptomatic classes, with isolation as the primary intervention, is formulated in this study. We establish the positivity and invariant region to ensure epidemiological relevance and derive the basic reproduction number, R0, as a threshold for disease persistence. The model analysis reveals that the diseasefree equilibrium is both locally and globally asymptotically…

Keywords
basic reproduction number equilibrium lyapunov function stability sensitivity analysis
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researchpp. 66–78

Discrete Mathematical Model of Fast Food Consumption: Control Approach

We investigate a discrete-time model, PLSCQ, to describe interactions among fast food consumer categories, among five population categories: potential consumers (P), moderate consumers (L), excessive consumers (S), obese individuals (C), and individuals who have ceased fast food consumption (Q). We seek for an optimal strategy that minimizes the excessive consumer and obese populations while maximizing the number of individuals who stop or recover. We incorporate three control measures, representing media and education for potential consumers, healthy eating campaigns for excessive consumers,…

Keywords
mathematical model fast food optimal control discrete-time non-linear system
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researchpp. 79–92

Multiscale Geographically and Temporally Weighted Regression with LASSO and Adaptive LASSO for Tuberculosis Incidence Mapping in West Java

Tuberculosis (TB) is a global health issue caused by Mycobacterium tuberculosis and can affect any organ of the body, especially the lungs. The trend of TB cases varies between regions, and analytic assessment is required to identify the predictor variables. The purpose of this research is to compare the Multiscale Geographically and Temporally Weighted Regression (MGTWR) and the Geographically and Temporally Weighted Regression (GTWR) method, which both use Gaussian, Exponential, Uniform, and Bi-Square kernel functions, to identify significant variables in each region annually. The MGTWR…

Keywords
disease mapping spatio-temporal variabel selection spatial statistics kernel function
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researchpp. 93–109

Mathematical Model of Dengue Transmission Dynamics with Adaptive Human Behavior

Dengue fever, a viral disease spread by Aedes mosquitoes, is a significant public health issue in tropical and subtropical regions. Behavioral adaptations in response to perceived infection risks can significantly reduce disease incidence and prevalence through the adoption of control measures. However, most existing models developed to assess the mitigation of dengue only implicitly account for this adaptive behavior within the dynamics of disease transmission. In this paper, we propose a mathematical model that explicitly incorporates adaptive human behavior in response to community…

Keywords
dengue behavioral change reproduction number sensitivity analysis
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